Epigenetic Alterations in Oncogenesis
Bilian Jin, Keith D. Robertson (auth.), Adam R. Karpf (eds.)The purpose of this book is to provide an up to date review of the nature and consequences of epigenetic changes in cancer. Epigenetics literally means “above” genetics, and consists of heritable gene expression or other phenotypic states not accounted for by DNA base sequence. Epigenetic changes are now known to make a large contribution to various aspects of tumorigenesis. These changes include alterations in global and promoter specific DNA methylation, activating and repressive histone modifications, and changes in higher order chromatin structures. Each of these topics will be covered in this book.
Категорії:
Рік:
2013
Видання:
1
Видавництво:
Springer-Verlag New York
Мова:
english
Сторінки:
348
ISBN 10:
1441999671
ISBN 13:
9781441999672
Серії:
Advances in Experimental Medicine and Biology 754
Файл:
PDF, 11.33 MB
IPFS:
,
english, 2013
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